BDBM50234034 CHEMBL4093860

SMILES: Fc1ccc(OC[C@H]2CCCN2c2ncnc3[nH]cnc23)cc1

InChI Key: InChIKey=IQRDKCVIPSPHJN-GFCCVEGCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein 2 (Homo sapiens (Human))	BDBM50234034 (CHEMBL4093860) Show SMILES Fc1ccc(OC[C@H]2CCCN2c2ncnc3[nH]cnc23)cc1 |r| Show InChI InChI=1S/C16H16FN5O/c17-11-3-5-13(6-4-11)23-8-12-2-1-7-22(12)16-14-15(19-9-18-14)20-10-21-16/h3-6,9-10,12H,1-2,7-8H2,(H,18,19,20,21)/t12-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His tagged MetAP-2 using tripeptide Met-Ala-Ser as substrate preincubated for 15 mins followed by substrat...				Bioorg Med Chem Lett 27: 551-556 (2017) BindingDB Entry DOI: 10.7270/Q2V98BB4
					More data for this Ligand-Target Pair