BDBM50234054 6-(6-Oxo-4-phenyl-1,6-dihydro-pyrimidin-2-ylsulfanyl)-hexanoic acid hydroxyamide::CHEMBL261831::N-hydroxy-6-(3,4-dihydro-4-oxo-6-phenyl-2-pyrimidinylthio)hexanamide::N-hydroxy-6-(6-oxo-4-phenyl-1,6-dihydropyrimidin-2-ylthio)hexanamide

SMILES: ONC(=O)CCCCCSc1nc(cc(=O)[nH]1)-c1ccccc1

InChI Key: InChIKey=YOKJODNAAKQIBZ-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50234054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD2 (Zea mays)	BDBM50234054 (6-(6-Oxo-4-phenyl-1,6-dihydro-pyrimidin-2-ylsulfan...) Show SMILES ONC(=O)CCCCCSc1nc(cc(=O)[nH]1)-c1ccccc1 Show InChI InChI=1S/C16H19N3O3S/c20-14(19-22)9-5-2-6-10-23-16-17-13(11-15(21)18-16)12-7-3-1-4-8-12/h1,3-4,7-8,11,22H,2,5-6,9-10H2,(H,19,20)(H,17,18,21)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against Histone deacetylase 2 in maize				Bioorg Med Chem Lett 15: 4656-61 (2005) Article DOI: 10.1016/j.bmcl.2005.07.081 BindingDB Entry DOI: 10.7270/Q29886JV
					More data for this Ligand-Target Pair
Histone deacetylase HD2 (Zea mays)	BDBM50234054 (6-(6-Oxo-4-phenyl-1,6-dihydro-pyrimidin-2-ylsulfan...) Show SMILES ONC(=O)CCCCCSc1nc(cc(=O)[nH]1)-c1ccccc1 Show InChI InChI=1S/C16H19N3O3S/c20-14(19-22)9-5-2-6-10-23-16-17-13(11-15(21)18-16)12-7-3-1-4-8-12/h1,3-4,7-8,11,22H,2,5-6,9-10H2,(H,19,20)(H,17,18,21)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize HD2				J Med Chem 49: 6046-56 (2006) Article DOI: 10.1021/jm0605536 BindingDB Entry DOI: 10.7270/Q2Z31Z9B
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Mus musculus (Mouse))	BDBM50234054 (6-(6-Oxo-4-phenyl-1,6-dihydro-pyrimidin-2-ylsulfan...) Show SMILES ONC(=O)CCCCCSc1nc(cc(=O)[nH]1)-c1ccccc1 Show InChI InChI=1S/C16H19N3O3S/c20-14(19-22)9-5-2-6-10-23-16-17-13(11-15(21)18-16)12-7-3-1-4-8-12/h1,3-4,7-8,11,22H,2,5-6,9-10H2,(H,19,20)(H,17,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Curated by ChEMBL					Assay Description Inhibition of mouse liver HDAC1				J Med Chem 51: 1505-29 (2008) Article DOI: 10.1021/jm7011408 BindingDB Entry DOI: 10.7270/Q2M32WMT
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Mus musculus (Mouse))	BDBM50234054 (6-(6-Oxo-4-phenyl-1,6-dihydro-pyrimidin-2-ylsulfan...) Show SMILES ONC(=O)CCCCCSc1nc(cc(=O)[nH]1)-c1ccccc1 Show InChI InChI=1S/C16H19N3O3S/c20-14(19-22)9-5-2-6-10-23-16-17-13(11-15(21)18-16)12-7-3-1-4-8-12/h1,3-4,7-8,11,22H,2,5-6,9-10H2,(H,19,20)(H,17,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of mouse HDAC1				J Med Chem 49: 6046-56 (2006) Article DOI: 10.1021/jm0605536 BindingDB Entry DOI: 10.7270/Q2Z31Z9B
					More data for this Ligand-Target Pair
Histone deacetylase HD1B (Zea mays)	BDBM50234054 (6-(6-Oxo-4-phenyl-1,6-dihydro-pyrimidin-2-ylsulfan...) Show SMILES ONC(=O)CCCCCSc1nc(cc(=O)[nH]1)-c1ccccc1 Show InChI InChI=1S/C16H19N3O3S/c20-14(19-22)9-5-2-6-10-23-16-17-13(11-15(21)18-16)12-7-3-1-4-8-12/h1,3-4,7-8,11,22H,2,5-6,9-10H2,(H,19,20)(H,17,18,21)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize HD1B				J Med Chem 49: 6046-56 (2006) Article DOI: 10.1021/jm0605536 BindingDB Entry DOI: 10.7270/Q2Z31Z9B
					More data for this Ligand-Target Pair