BDBM50234079 CHEMBL4096048
SMILES: Cc1ccc(NC(=O)c2ccc3OCCOc3c2)cc1NC(=O)c1ccc2NCCCc2c1
InChI Key: InChIKey=LLTXIVYBCVSFHB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Pirin (Homo sapiens (Human)) | BDBM50234079 (CHEMBL4096048) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of bisamide probe binding to pirin in human SKOV3 cells by SILAC-based quantitative mass spectrometry pull down assay | J Med Chem 60: 180-201 (2017) BindingDB Entry DOI: 10.7270/Q2KW5J9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat shock factor protein 1 (Homo sapiens (Human)) | BDBM50234079 (CHEMBL4096048) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 224 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi... | J Med Chem 60: 180-201 (2017) BindingDB Entry DOI: 10.7270/Q2KW5J9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat shock factor protein 1 (Homo sapiens (Human)) | BDBM50234079 (CHEMBL4096048) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi... | J Med Chem 60: 180-201 (2017) BindingDB Entry DOI: 10.7270/Q2KW5J9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pirin (Homo sapiens (Human)) | BDBM50234079 (CHEMBL4096048) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Binding affinity to recombinant human pirin by surface plasma resonance method | J Med Chem 60: 180-201 (2017) BindingDB Entry DOI: 10.7270/Q2KW5J9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pirin (Homo sapiens (Human)) | BDBM50234079 (CHEMBL4096048) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Binding affinity to recombinant human pirin by surface plasma resonance method | J Med Chem 60: 180-201 (2017) BindingDB Entry DOI: 10.7270/Q2KW5J9D | |||||||||||
More data for this Ligand-Target Pair |