BDBM50234295 CHEMBL4080569

SMILES: CS(=O)(=O)N1CCC[C@@H](C1)c1csc(n1)-c1ccccc1NC(=O)c1nc(c[nH]1)C#N

InChI Key: InChIKey=TZAUCXMBRSNQFL-ZDUSSCGKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234295   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50234295 (CHEMBL4080569) Show SMILES CS(=O)(=O)N1CCC[C@@H](C1)c1csc(n1)-c1ccccc1NC(=O)c1nc(c[nH]1)C#N |r| Show InChI InChI=1S/C20H20N6O3S2/c1-31(28,29)26-8-4-5-13(11-26)17-12-30-20(25-17)15-6-2-3-7-16(15)24-19(27)18-22-10-14(9-21)23-18/h2-3,6-7,10,12-13H,4-5,8,11H2,1H3,(H,22,23)(H,24,27)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Takeda California Curated by ChEMBL					Assay Description Inhibition of Axl (unknown origin)				Bioorg Med Chem Lett 27: 1099-1104 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q6F
					More data for this Ligand-Target Pair