BDBM50234302 CHEMBL4086393

SMILES: CS(=O)(=O)N1CCO[C@@H](C1)c1csc(n1)-c1ccccc1NC(=O)c1ncc[nH]1

InChI Key: InChIKey=MPCBXJASUBLGMA-HNNXBMFYSA-N

Data: 1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50234302 (CHEMBL4086393) Show SMILES CS(=O)(=O)N1CCO[C@@H](C1)c1csc(n1)-c1ccccc1NC(=O)c1ncc[nH]1 |r| Show InChI InChI=1S/C18H19N5O4S2/c1-29(25,26)23-8-9-27-15(10-23)14-11-28-18(22-14)12-4-2-3-5-13(12)21-17(24)16-19-6-7-20-16/h2-7,11,15H,8-10H2,1H3,(H,19,20)(H,21,24)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a
Takeda California Curated by ChEMBL					Assay Description Inhibition of Axl (unknown origin) phosphorylation expressed in HEK293 cells by ELISA				Bioorg Med Chem Lett 27: 1099-1104 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q6F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50234302 (CHEMBL4086393) Show SMILES CS(=O)(=O)N1CCO[C@@H](C1)c1csc(n1)-c1ccccc1NC(=O)c1ncc[nH]1 |r| Show InChI InChI=1S/C18H19N5O4S2/c1-29(25,26)23-8-9-27-15(10-23)14-11-28-18(22-14)12-4-2-3-5-13(12)21-17(24)16-19-6-7-20-16/h2-7,11,15H,8-10H2,1H3,(H,19,20)(H,21,24)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Takeda California Curated by ChEMBL					Assay Description Inhibition of Axl (unknown origin)				Bioorg Med Chem Lett 27: 1099-1104 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q6F
					More data for this Ligand-Target Pair