BDBM50234347 CHEMBL4073763

SMILES: CC(OC(C)=O)c1nc(c(Sc2c(Cl)cncc2Cl)s1)[N+]([O-])=O

InChI Key: InChIKey=CJXCRADCCGMMQS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234347   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50234347 (CHEMBL4073763) Show SMILES CC(OC(C)=O)c1nc(c(Sc2c(Cl)cncc2Cl)s1)[N+]([O-])=O Show InChI InChI=1S/C12H9Cl2N3O4S2/c1-5(21-6(2)18)11-16-10(17(19)20)12(23-11)22-9-7(13)3-15-4-8(9)14/h3-5H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of USP7 (unknown origin) using Ub-Rho as substrate preincubated for 30 mins followed by substrate addition and subsequent incubation in da...				Bioorg Med Chem Lett 27: 845-849 (2017) BindingDB Entry DOI: 10.7270/Q20Z75HQ
					More data for this Ligand-Target Pair