BDBM50234353 CHEMBL4087728

SMILES: Cc1ccc(CNC(=O)c2nc(c(Sc3c(Cl)cncc3Cl)s2)[N+]([O-])=O)cc1

InChI Key: InChIKey=UATUJLNJCBJVIX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234353   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50234353 (CHEMBL4087728) Show SMILES Cc1ccc(CNC(=O)c2nc(c(Sc3c(Cl)cncc3Cl)s2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C17H12Cl2N4O3S2/c1-9-2-4-10(5-3-9)6-21-15(24)16-22-14(23(25)26)17(28-16)27-13-11(18)7-20-8-12(13)19/h2-5,7-8H,6H2,1H3,(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of USP7 (unknown origin) using Ub-Rho as substrate preincubated for 30 mins followed by substrate addition and subsequent incubation in da...				Bioorg Med Chem Lett 27: 845-849 (2017) BindingDB Entry DOI: 10.7270/Q20Z75HQ
					More data for this Ligand-Target Pair