BindingDB PrimarySearch

BDBM50234567 1,4-dideoxy-1,4-imino-D-ribitol::CHEMBL261634::IMINORIBITOL

SMILES: OC[C@H]1NC[C@H](O)[C@@H]1O

InChI Key: InChIKey=OQEBIHBLFRADNM-MROZADKFSA-N

Data: 3 KI 4 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50234567
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (Homo sapiens (Human))	BDBM50234567 (1,4-dideoxy-1,4-imino-D-ribitol \| CHEMBL261634 \| I...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H]1O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Porto 687 Curated by ChEMBL					Assay Description Inhibition of human ER alpha mannosidase 1				Bioorg Med Chem 20: 6945-59 (2012) Article DOI: 10.1016/j.bmc.2012.10.011 BindingDB Entry DOI: 10.7270/Q26T0NTC
Universidade do Porto 687 Curated by ChEMBL					More data for this Ligand-Target Pair
IAG-nucleoside hydrolase (Trypanosoma vivax)	BDBM50234567 (1,4-dideoxy-1,4-imino-D-ribitol \| CHEMBL261634 \| I...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H]1O \|r\| Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma vivax IAG-nucleoside hydrolase expressed in Escherichia coli WK6				Eur J Med Chem 43: 315-26 (2008) Article DOI: 10.1016/j.ejmech.2007.03.027 BindingDB Entry DOI: 10.7270/Q28P61FH
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Golgi alpha-mannosidase II (Homo sapiens (Human))	BDBM50234567 (1,4-dideoxy-1,4-imino-D-ribitol \| CHEMBL261634 \| I...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H]1O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.43E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Porto 687 Curated by ChEMBL					Assay Description Inhibition of human golgi alpha mannosidase 2				Bioorg Med Chem 20: 6945-59 (2012) Article DOI: 10.1016/j.bmc.2012.10.011 BindingDB Entry DOI: 10.7270/Q26T0NTC
Universidade do Porto 687 Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-mannosidase (Rattus norvegicus)	BDBM50234567 (1,4-dideoxy-1,4-imino-D-ribitol \| CHEMBL261634 \| I...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H]1O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of rat epididymis beta-mannosidase assessed as p-nitrophenol release by spectrophotometrically				J Nat Prod 65: 198-202 (2002) BindingDB Entry DOI: 10.7270/Q2ZW1KN6
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase) (Rattus norvegicus (Rat))	BDBM50234567 (1,4-dideoxy-1,4-imino-D-ribitol \| CHEMBL261634 \| I...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H]1O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of rat intestinal isomaltase assessed as glucose release by Glucose B-test				J Nat Prod 65: 198-202 (2002) BindingDB Entry DOI: 10.7270/Q2ZW1KN6
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase) (Rattus norvegicus (Rat))	BDBM50234567 (1,4-dideoxy-1,4-imino-D-ribitol \| CHEMBL261634 \| I...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H]1O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	9.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of rat intestinal sucrase assessed as glucose release by Glucose B-test				J Nat Prod 65: 198-202 (2002) BindingDB Entry DOI: 10.7270/Q2ZW1KN6
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
β-galactosidase (Bos taurus (Bovine))	BDBM50234567 (1,4-dideoxy-1,4-imino-D-ribitol \| CHEMBL261634 \| I...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H]1O \|r\| Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-galactosidase assessed as p-nitrophenol release by spectrophotometrically				J Nat Prod 65: 198-202 (2002) BindingDB Entry DOI: 10.7270/Q2ZW1KN6
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair