BDBM50234678 CHEMBL4098742

SMILES: CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(NC1CCCC1)c1nnnn1-c1cccc(OCc2ccccc2)c1

InChI Key: InChIKey=TVJBWILQPHHDJE-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50234678 (CHEMBL4098742) Show SMILES CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(NC1CCCC1)c1nnnn1-c1cccc(OCc2ccccc2)c1 Show InChI InChI=1S/C31H31ClN6O3/c1-2-40-31(39)29-27(25-16-15-21(32)17-26(25)34-29)28(33-22-11-6-7-12-22)30-35-36-37-38(30)23-13-8-14-24(18-23)41-19-20-9-4-3-5-10-20/h3-5,8-10,13-18,22,28,33-34H,2,6-7,11-12,19H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of 5'--FAM-LTFEHYWAQLTS peptide binding to N-terminal domain human MDM2 (1 to 118 residues) expressed in Escherichia coli BL21(DE3) measur...				Eur J Med Chem 126: 384-407 (2017) BindingDB Entry DOI: 10.7270/Q2JQ1381
					More data for this Ligand-Target Pair
p53-Binding Protein HDMX (Homo sapiens (Human))	BDBM50234678 (CHEMBL4098742) Show SMILES CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(NC1CCCC1)c1nnnn1-c1cccc(OCc2ccccc2)c1 Show InChI InChI=1S/C31H31ClN6O3/c1-2-40-31(39)29-27(25-16-15-21(32)17-26(25)34-29)28(33-22-11-6-7-12-22)30-35-36-37-38(30)23-13-8-14-24(18-23)41-19-20-9-4-3-5-10-20/h3-5,8-10,13-18,22,28,33-34H,2,6-7,11-12,19H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of 5'--FAM-LTFEHYWAQLTS peptide binding to N-terminal domain human MDMX (1 to 134 residues) measured after 15 mins by fluorescence polariz...				Eur J Med Chem 126: 384-407 (2017) BindingDB Entry DOI: 10.7270/Q2JQ1381
					More data for this Ligand-Target Pair