BDBM50234680 CHEMBL4100330

SMILES: CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(Cl)cc1

InChI Key: InChIKey=CAMQOPRFLNGXAS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p53-Binding Protein HDMX (Homo sapiens (Human))	BDBM50234680 (CHEMBL4100330) Show SMILES CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H28Cl2N6O2/c1-2-36-26(35)24-22(20-13-10-18(28)14-21(20)30-24)23(29-15-16-6-4-3-5-7-16)25-31-32-33-34(25)19-11-8-17(27)9-12-19/h8-14,16,23,29-30H,2-7,15H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of 5'--FAM-LTFEHYWAQLTS peptide binding to N-terminal domain human MDMX (1 to 134 residues) measured after 15 mins by fluorescence polariz...				Eur J Med Chem 126: 384-407 (2017) BindingDB Entry DOI: 10.7270/Q2JQ1381
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50234680 (CHEMBL4100330) Show SMILES CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H28Cl2N6O2/c1-2-36-26(35)24-22(20-13-10-18(28)14-21(20)30-24)23(29-15-16-6-4-3-5-7-16)25-31-32-33-34(25)19-11-8-17(27)9-12-19/h8-14,16,23,29-30H,2-7,15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.17E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of 5'--FAM-LTFEHYWAQLTS peptide binding to N-terminal domain human MDM2 (1 to 118 residues) expressed in Escherichia coli BL21(DE3) measur...				Eur J Med Chem 126: 384-407 (2017) BindingDB Entry DOI: 10.7270/Q2JQ1381
					More data for this Ligand-Target Pair