BDBM50234716 CHEMBL4104441

SMILES: Cc1ccc(cc1)-c1[nH]c2ccc(NC(=O)C(F)(F)F)cc2c(=O)c1-c1ccc(C)cc1

InChI Key: InChIKey=SRGUHRCIZYWNIM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234716   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Intestinal alkaline phosphatase (Bos taurus (Cattle))	BDBM50234716 (CHEMBL4104441) Show SMILES Cc1ccc(cc1)-c1[nH]c2ccc(NC(=O)C(F)(F)F)cc2c(=O)c1-c1ccc(C)cc1 Show InChI InChI=1S/C25H19F3N2O2/c1-14-3-7-16(8-4-14)21-22(17-9-5-15(2)6-10-17)30-20-12-11-18(13-19(20)23(21)31)29-24(32)25(26,27)28/h3-13H,1-2H3,(H,29,32)(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of calf intestinal alkaline phosphatase using CDP-star as substrate preincubated for 5 to 7 mins followed by substrate addition measured a...				Eur J Med Chem 126: 408-420 (2017) BindingDB Entry DOI: 10.7270/Q2DZ0BKR
					More data for this Ligand-Target Pair
Tissue non-specific alkaline phosphatase (TNAP) (Bos taurus (Cattle))	BDBM50234716 (CHEMBL4104441) Show SMILES Cc1ccc(cc1)-c1[nH]c2ccc(NC(=O)C(F)(F)F)cc2c(=O)c1-c1ccc(C)cc1 Show InChI InChI=1S/C25H19F3N2O2/c1-14-3-7-16(8-4-14)21-22(17-9-5-15(2)6-10-17)30-20-12-11-18(13-19(20)23(21)31)29-24(32)25(26,27)28/h3-13H,1-2H3,(H,29,32)(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of bovine TNAP using CDP-star as substrate preincubated for 5 to 7 mins followed by substrate addition measured after 15 mins by spectroph...				Eur J Med Chem 126: 408-420 (2017) BindingDB Entry DOI: 10.7270/Q2DZ0BKR
					More data for this Ligand-Target Pair