BDBM50234790 (E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde oxime::3-chloro-4-(4-hydroxyphenyl)salicylaldoxime::CHEMBL405154

SMILES: Oc1ccc(cc1)-c1ccc(CN=O)c(O)c1Cl

InChI Key: InChIKey=CIYDFCOZUPKHFA-UHFFFAOYSA-N

Data: 2 KI  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50234790   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50234790 ((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...) Show SMILES Oc1ccc(cc1)-c1ccc(CN=O)c(O)c1Cl Show InChI InChI=1S/C13H10ClNO3/c14-12-11(8-1-4-10(16)5-2-8)6-3-9(7-15-18)13(12)17/h1-6,16-17H,7H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]estradiol from purified full length human ERbeta receptor				J Med Chem 51: 1344-51 (2008) Article DOI: 10.1021/jm701396g BindingDB Entry DOI: 10.7270/Q2HQ40SB
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50234790 ((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...) Show SMILES Oc1ccc(cc1)-c1ccc(CN=O)c(O)c1Cl Show InChI InChI=1S/C13H10ClNO3/c14-12-11(8-1-4-10(16)5-2-8)6-3-9(7-15-18)13(12)17/h1-6,16-17H,7H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]estradiol from purified full length human ERalpha receptor				J Med Chem 51: 1344-51 (2008) Article DOI: 10.1021/jm701396g BindingDB Entry DOI: 10.7270/Q2HQ40SB
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50234790 ((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...) Show SMILES Oc1ccc(cc1)-c1ccc(CN=O)c(O)c1Cl Show InChI InChI=1S/C13H10ClNO3/c14-12-11(8-1-4-10(16)5-2-8)6-3-9(7-15-18)13(12)17/h1-6,16-17H,7H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Universita di Pisa Curated by ChEMBL					Assay Description Agonist activity at full-length human estrogen receptor alpha expressed in human HEC1 cells assessed as transcriptional activation after 24 hrs by lu...				J Med Chem 52: 858-67 (2009) Article DOI: 10.1021/jm801458t BindingDB Entry DOI: 10.7270/Q23R0SRH
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50234790 ((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...) Show SMILES Oc1ccc(cc1)-c1ccc(CN=O)c(O)c1Cl Show InChI InChI=1S/C13H10ClNO3/c14-12-11(8-1-4-10(16)5-2-8)6-3-9(7-15-18)13(12)17/h1-6,16-17H,7H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Universita di Pisa Curated by ChEMBL					Assay Description Agonist activity at full-length human estrogen receptor alpha expressed in human HEC1 cells assessed as transcriptional activation after 24 hrs by lu...				J Med Chem 52: 858-67 (2009) Article DOI: 10.1021/jm801458t BindingDB Entry DOI: 10.7270/Q23R0SRH
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50234790 ((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...) Show SMILES Oc1ccc(cc1)-c1ccc(CN=O)c(O)c1Cl Show InChI InChI=1S/C13H10ClNO3/c14-12-11(8-1-4-10(16)5-2-8)6-3-9(7-15-18)13(12)17/h1-6,16-17H,7H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Universita di Pisa Curated by ChEMBL					Assay Description Agonist activity at full length human ERalpha receptor expressed in human HEC-1 cells assessed as (ERE)2-pS2-luc reporter gene transcriptional activi...				J Med Chem 51: 1344-51 (2008) Article DOI: 10.1021/jm701396g BindingDB Entry DOI: 10.7270/Q2HQ40SB
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50234790 ((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...) Show SMILES Oc1ccc(cc1)-c1ccc(CN=O)c(O)c1Cl Show InChI InChI=1S/C13H10ClNO3/c14-12-11(8-1-4-10(16)5-2-8)6-3-9(7-15-18)13(12)17/h1-6,16-17H,7H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Universita di Pisa Curated by ChEMBL					Assay Description Agonist activity at full length human ERbeta receptor expressed in human HEC-1 cells assessed as (ERE)2-pS2-luc reporter gene transcriptional activit...				J Med Chem 51: 1344-51 (2008) Article DOI: 10.1021/jm701396g BindingDB Entry DOI: 10.7270/Q2HQ40SB
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50234790 ((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...) Show SMILES Oc1ccc(cc1)-c1ccc(CN=O)c(O)c1Cl Show InChI InChI=1S/C13H10ClNO3/c14-12-11(8-1-4-10(16)5-2-8)6-3-9(7-15-18)13(12)17/h1-6,16-17H,7H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Universita di Pisa Curated by ChEMBL					Assay Description Agonist activity at full-length human estrogen receptor beta expressed in human HEC1 cells assessed as transcriptional activation after 24 hrs by luc...				J Med Chem 52: 858-67 (2009) Article DOI: 10.1021/jm801458t BindingDB Entry DOI: 10.7270/Q23R0SRH
					More data for this Ligand-Target Pair