BDBM50234810 CHEMBL4065167
SMILES: CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(\C=C\c3ccccc3)o2)c1
InChI Key: InChIKey=YIEXHVPVWYOPCC-MDZDMXLPSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-Dependent Kinase 9 (CDK9) (Homo sapiens (Human)) | BDBM50234810 (CHEMBL4065167) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of CDK9/CyclinT (unknown origin) using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation counting | Eur J Med Chem 126: 754-761 (2017) BindingDB Entry DOI: 10.7270/Q2S75JJV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human)) | BDBM50234810 (CHEMBL4065167) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of DYRK1A (unknown origin) using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation counting | Eur J Med Chem 126: 754-761 (2017) BindingDB Entry DOI: 10.7270/Q2S75JJV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase CLK1/CLK4 (Homo sapiens (Human)) | BDBM50234810 (CHEMBL4065167) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of human CLK1 using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation counting | Eur J Med Chem 126: 754-761 (2017) BindingDB Entry DOI: 10.7270/Q2S75JJV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50234810 (CHEMBL4065167) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of GSK3 alpha/beta (unknown origin) using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation counting | Eur J Med Chem 126: 754-761 (2017) BindingDB Entry DOI: 10.7270/Q2S75JJV | |||||||||||
More data for this Ligand-Target Pair |