BDBM50234934 CHEMBL4095646

SMILES: Cn1ncc(NCc2ccccc2)c(Cl)c1=O

InChI Key: InChIKey=JATQFCGMMLNIJW-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234934   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT2A/KAT2B (Homo sapiens (Human))	BDBM50234934 (CHEMBL4095646) Show SMILES Cn1ncc(NCc2ccccc2)c(Cl)c1=O Show InChI InChI=1S/C12H12ClN3O/c1-16-12(17)11(13)10(8-15-16)14-7-9-5-3-2-4-6-9/h2-6,8,14H,7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of GSK3103956A from FLAG-6 His-Halo tagged human PCAF bromodomain (715 to 831 residues) incubated for 30 mins in dark by TR-FRET assay				J Med Chem 60: 695-709 (2017) BindingDB Entry DOI: 10.7270/Q2W09863
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50234934 (CHEMBL4095646) Show SMILES Cn1ncc(NCc2ccccc2)c(Cl)c1=O Show InChI InChI=1S/C12H12ClN3O/c1-16-12(17)11(13)10(8-15-16)14-7-9-5-3-2-4-6-9/h2-6,8,14H,7H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Binding affinity to BRD4 (1) (unknown origin) N-terminal bromodomain by TR-FRET assay				J Med Chem 63: 5816-5840 (2020)
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2A/KAT2B (Homo sapiens (Human))	BDBM50234934 (CHEMBL4095646) Show SMILES Cn1ncc(NCc2ccccc2)c(Cl)c1=O Show InChI InChI=1S/C12H12ClN3O/c1-16-12(17)11(13)10(8-15-16)14-7-9-5-3-2-4-6-9/h2-6,8,14H,7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Binding affinity to PCAF (unknown origin) N-terminal bromodomain by TR-FRET assay				J Med Chem 63: 5816-5840 (2020)
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Homo sapiens (Human))	BDBM50234934 (CHEMBL4095646) Show SMILES Cn1ncc(NCc2ccccc2)c(Cl)c1=O Show InChI InChI=1S/C12H12ClN3O/c1-16-12(17)11(13)10(8-15-16)14-7-9-5-3-2-4-6-9/h2-6,8,14H,7H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Binding affinity to BRD9 (unknown origin) N-terminal bromodomain by TR-FRET assay				J Med Chem 63: 5816-5840 (2020)
					More data for this Ligand-Target Pair