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SMILES: CN1c2ccccc2N(Cc2ccccc2)C[C@@H](NC(=O)[C@@H](Cc2ccccc2F)NC(=O)OC(C)(C)C)C1=O

InChI Key: InChIKey=TYLQJNXEEPKAOZ-JWQCQUIFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235499   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM50235499
PNG
(CHEMBL438869 | tert-butyl (R)-1-((R)-5-benzyl-1-me...)
Show SMILES CN1c2ccccc2N(Cc2ccccc2)C[C@@H](NC(=O)[C@@H](Cc2ccccc2F)NC(=O)OC(C)(C)C)C1=O
Show InChI InChI=1S/C31H35FN4O4/c1-31(2,3)40-30(39)34-24(18-22-14-8-9-15-23(22)32)28(37)33-25-20-36(19-21-12-6-5-7-13-21)27-17-11-10-16-26(27)35(4)29(25)38/h5-17,24-25H,18-20H2,1-4H3,(H,33,37)(H,34,39)/t24-,25-/m1/s1
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KEGG

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Similars
Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human Nav1.7 sodium channel expressed in HEK293 cells by FRET assay

Bioorg Med Chem Lett 18: 1963-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.123
BindingDB Entry DOI: 10.7270/Q24T6J4T
More data for this
Ligand-Target Pair