BDBM50235629 CHEMBL4063970

SMILES: CN(C)[C@H]1CN(Cc2nccn2C)C[C@@H]1c1cn(C)c2ccccc12

InChI Key: InChIKey=VRQHCKQZNPAZPR-MJGOQNOKSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (EED) (Homo sapiens (Human))	BDBM50235629 (CHEMBL4063970) Show SMILES CN(C)[C@H]1CN(Cc2nccn2C)C[C@@H]1c1cn(C)c2ccccc12 |r| Show InChI InChI=1S/C20H27N5/c1-22(2)19-13-25(14-20-21-9-10-23(20)3)12-17(19)16-11-24(4)18-8-6-5-7-15(16)18/h5-11,17,19H,12-14H2,1-4H3/t17-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of OG(488) labeled probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assay				Bioorg Med Chem Lett 27: 1576-1583 (2017) Article DOI: 10.1016/j.bmcl.2017.02.030 BindingDB Entry DOI: 10.7270/Q22F7QQG
					More data for this Ligand-Target Pair