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BDBM50235636 CHEMBL4104796

SMILES: CN(C)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1C1CCOCC1

InChI Key: InChIKey=HPMRAVHHRVIMFH-KDOFPFPSSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235636   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polycomb protein EED (EED)


(Homo sapiens (Human))		BDBM50235636
PNG
(CHEMBL4104796)
Show SMILES CN(C)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1C1CCOCC1 |r|
Show InChI InChI=1S/C18H26BrFN2O/c1-21(2)18-12-22(10-14(18)13-6-8-23-9-7-13)11-15-16(19)4-3-5-17(15)20/h3-5,13-14,18H,6-12H2,1-2H3/t14-,18+/m1/s1
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Similars
Article
PubMed
 59n/an/an/an/an/an/an/an/a



AbbVie Inc.

Curated by ChEMBL


Assay Description
Inhibition of OG(488) labeled probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assay

Bioorg Med Chem Lett 27: 1576-1583 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.030
BindingDB Entry DOI: 10.7270/Q22F7QQG
More data for this
Ligand-Target Pair