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BDBM50235638 CHEMBL4104253

SMILES: CN(C)[C@H]1CN(Cc2cc(C)ccc2F)C[C@@H]1c1cn(C)c2ccccc12

InChI Key: InChIKey=OGKGBQXQHIIVRY-OFNKIYASSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235638   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polycomb protein EED (EED)


(Homo sapiens (Human))		BDBM50235638
PNG
(CHEMBL4104253)
Show SMILES CN(C)[C@H]1CN(Cc2cc(C)ccc2F)C[C@@H]1c1cn(C)c2ccccc12 |r|
Show InChI InChI=1S/C23H28FN3/c1-16-9-10-21(24)17(11-16)12-27-14-20(23(15-27)25(2)3)19-13-26(4)22-8-6-5-7-18(19)22/h5-11,13,20,23H,12,14-15H2,1-4H3/t20-,23+/m1/s1
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Article
PubMed
 160n/an/an/an/an/an/an/an/a



AbbVie Inc.

Curated by ChEMBL


Assay Description
Inhibition of OG(488) labeled probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assay

Bioorg Med Chem Lett 27: 1576-1583 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.030
BindingDB Entry DOI: 10.7270/Q22F7QQG
More data for this
Ligand-Target Pair