BDBM50235825 CHEMBL4065615

SMILES: CCCNc1nc(Nc2ccc3c(NC(=O)COC3(C)C)c2)nc2ccoc12

InChI Key: InChIKey=OKSGKOXMFAYXPQ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50235825 (CHEMBL4065615) Show SMILES CCCNc1nc(Nc2ccc3c(NC(=O)COC3(C)C)c2)nc2ccoc12 Show InChI InChI=1S/C20H23N5O3/c1-4-8-21-18-17-14(7-9-27-17)24-19(25-18)22-12-5-6-13-15(10-12)23-16(26)11-28-20(13,2)3/h5-7,9-10H,4,8,11H2,1-3H3,(H,23,26)(H2,21,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
AbbVie Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated platelets				Bioorg Med Chem Lett 26: 5562-5567 (2016) Article DOI: 10.1016/j.bmcl.2016.09.077 BindingDB Entry DOI: 10.7270/Q2WQ061V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50235825 (CHEMBL4065615) Show SMILES CCCNc1nc(Nc2ccc3c(NC(=O)COC3(C)C)c2)nc2ccoc12 Show InChI InChI=1S/C20H23N5O3/c1-4-8-21-18-17-14(7-9-27-17)24-19(25-18)22-12-5-6-13-15(10-12)23-16(26)11-28-20(13,2)3/h5-7,9-10H,4,8,11H2,1-3H3,(H,23,26)(H2,21,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged Syk catalytic domain (356 to 635 residues) (unknown origin) using biotin-TYR1 as substrate after 60 mins by TR-FR...				Bioorg Med Chem Lett 26: 5562-5567 (2016) Article DOI: 10.1016/j.bmcl.2016.09.077 BindingDB Entry DOI: 10.7270/Q2WQ061V
					More data for this Ligand-Target Pair