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SMILES: CC[C@H](C)Nc1nc2ccc(cc2s1)-c1c(N)[nH]nc1-c1ccccc1F

InChI Key: InChIKey=KRMVYKOLDJOYLK-NSHDSACASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235894   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50235894
PNG
(6-(5-amino-3-(2-fluorophenyl)-1H-pyrazol-4-yl)-N-(...)
Show SMILES CC[C@H](C)Nc1nc2ccc(cc2s1)-c1c(N)[nH]nc1-c1ccccc1F
Show InChI InChI=1S/C20H20FN5S/c1-3-11(2)23-20-24-15-9-8-12(10-16(15)27-20)17-18(25-26-19(17)22)13-6-4-5-7-14(13)21/h4-11H,3H2,1-2H3,(H,23,24)(H3,22,25,26)/t11-/m0/s1
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PC cid
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Similars
Article
PubMed
n/an/a 5.5n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of p38alpha

Bioorg Med Chem Lett 18: 1874-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.011
BindingDB Entry DOI: 10.7270/Q2H41R5C
More data for this
Ligand-Target Pair