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SMILES: CC[C@@H](C)Nc1nc2ccc(cc2s1)-c1c(N)n(C)nc1-c1ccccc1F

InChI Key: InChIKey=CIJFZUZLHQTARE-GFCCVEGCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235900   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50235900
PNG
(6-(5-amino-3-(2-fluorophenyl)-1-methyl-1H-pyrazol-...)
Show SMILES CC[C@@H](C)Nc1nc2ccc(cc2s1)-c1c(N)n(C)nc1-c1ccccc1F
Show InChI InChI=1S/C21H22FN5S/c1-4-12(2)24-21-25-16-10-9-13(11-17(16)28-21)18-19(26-27(3)20(18)23)14-7-5-6-8-15(14)22/h5-12H,4,23H2,1-3H3,(H,24,25)/t12-/m1/s1
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Article
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n/an/a 11n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of p38alpha

Bioorg Med Chem Lett 18: 1874-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.011
BindingDB Entry DOI: 10.7270/Q2H41R5C
More data for this
Ligand-Target Pair