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SMILES: CC[C@@H](C)Nc1nc2ccc(cc2s1)-c1[nH]cnc1-c1ccccc1F

InChI Key: InChIKey=OJQSRRCUFRRNTP-GFCCVEGCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235904   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50235904
PNG
(CHEMBL439238 | N-(R)-sec-butyl-6-(4-(2-fluoropheny...)
Show SMILES CC[C@@H](C)Nc1nc2ccc(cc2s1)-c1[nH]cnc1-c1ccccc1F
Show InChI InChI=1S/C20H19FN4S/c1-3-12(2)24-20-25-16-9-8-13(10-17(16)26-20)18-19(23-11-22-18)14-6-4-5-7-15(14)21/h4-12H,3H2,1-2H3,(H,22,23)(H,24,25)/t12-/m1/s1
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Similars
Article
PubMed
n/an/a 1.60n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of p38alpha

Bioorg Med Chem Lett 18: 1874-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.011
BindingDB Entry DOI: 10.7270/Q2H41R5C
More data for this
Ligand-Target Pair