BDBM50236061 (R)-3-(2-(1-(3-fluoro-4-methoxyphenyl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide::CHEMBL254173

SMILES: CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(OC)c(F)c1

InChI Key: InChIKey=JYTMUJIPYPATSA-OAHLLOKOSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236061   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236061 ((R)-3-(2-(1-(3-fluoro-4-methoxyphenyl)propylamino)...) Show SMILES CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(OC)c(F)c1 Show InChI InChI=1S/C23H24FN3O5/c1-5-15(12-9-10-17(32-4)14(24)11-12)25-18-19(22(30)21(18)29)26-16-8-6-7-13(20(16)28)23(31)27(2)3/h6-11,15,25-26,28H,5H2,1-4H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IL8 from human CXCR2 by SPA assay				Bioorg Med Chem Lett 18: 1864-8 (2008) Article DOI: 10.1016/j.bmcl.2008.02.010 BindingDB Entry DOI: 10.7270/Q2CC10DK
					More data for this Ligand-Target Pair