BDBM50236213 2-(3-Benzylureido)Benzoic Acid::CHEMBL561499

SMILES: OC(=O)c1ccccc1NC(=O)NCc1ccccc1

InChI Key: InChIKey=QCLRLHJAKXQKSY-UHFFFAOYSA-N

Data: 1 KI  1 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM50236213 (2-(3-Benzylureido)Benzoic Acid | CHEMBL561499) Show SMILES OC(=O)c1ccccc1NC(=O)NCc1ccccc1 Show InChI InChI=1S/C15H14N2O3/c18-14(19)12-8-4-5-9-13(12)17-15(20)16-10-11-6-2-1-3-7-11/h1-9H,10H2,(H,18,19)(H2,16,17,20)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lavis Curated by ChEMBL					Assay Description Binding affinity to factor D (unknown origin) by 19F-NMR spectroscopy				J Med Chem 62: 2218-2244 (2019) Article DOI: 10.1021/acs.jmedchem.8b01210
					More data for this Ligand-Target Pair				3D Structure (crystal)
Complement factor D (Homo sapiens (Human))	BDBM50236213 (2-(3-Benzylureido)Benzoic Acid | CHEMBL561499) Show SMILES OC(=O)c1ccccc1NC(=O)NCc1ccccc1 Show InChI InChI=1S/C15H14N2O3/c18-14(19)12-8-4-5-9-13(12)17-15(20)16-10-11-6-2-1-3-7-11/h1-9H,10H2,(H,18,19)(H2,16,17,20)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Displacement of [19F]-Methyl (S)-2-((2-((3-(Trifluoromethoxy)phenyl)carbamoyl)-pyrrolidine-1-carboxamido)methyl)benzoate from recombinant human compl...				J Med Chem 60: 1946-1958 (2017) Article DOI: 10.1021/acs.jmedchem.6b01684 BindingDB Entry DOI: 10.7270/Q2ZG6VHG
					More data for this Ligand-Target Pair				3D Structure (crystal)