BDBM50236242 CHEMBL4093237

SMILES: COc1ccc(cc1C)C(=O)N1CC(CC(F)(F)C1)c1cc(C)nc2ncnn12

InChI Key: InChIKey=IQFKBXVRSUXQJZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236242   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50236242 (CHEMBL4093237) Show SMILES COc1ccc(cc1C)C(=O)N1CC(CC(F)(F)C1)c1cc(C)nc2ncnn12 Show InChI InChI=1S/C20H21F2N5O2/c1-12-6-14(4-5-17(12)29-3)18(28)26-9-15(8-20(21,22)10-26)16-7-13(2)25-19-23-11-24-27(16)19/h4-7,11,15H,8-10H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Dart Neuroscience LLC Curated by ChEMBL					Assay Description Inhibition of human full length GST-tagged PDE2a using FAM-labeled cAMP as substrate preincubated for 5 mins followed by substrate addition measured ...				J Med Chem 60: 2037-2051 (2017) Article DOI: 10.1021/acs.jmedchem.6b01793 BindingDB Entry DOI: 10.7270/Q2Q242GF
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