BindingDB logo
myBDB logout

null

SMILES: Fc1ccc(cc1)-c1[nH]c2ccc(cc2c1CCNC(=O)NS(=O)(=O)c1ccccc1Cl)C#N

InChI Key: InChIKey=DIHOHCOABOMUCZ-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236299   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50236299
PNG
(1-(2-chlorophenylsulfonyl)-3-(2-(5-cyano-2-(4-fluo...)
Show SMILES Fc1ccc(cc1)-c1[nH]c2ccc(cc2c1CCNC(=O)NS(=O)(=O)c1ccccc1Cl)C#N
Show InChI InChI=1S/C24H18ClFN4O3S/c25-20-3-1-2-4-22(20)34(32,33)30-24(31)28-12-11-18-19-13-15(14-27)5-10-21(19)29-23(18)16-6-8-17(26)9-7-16/h1-10,13,29H,11-12H2,(H2,28,30,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 400n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay

Bioorg Med Chem Lett 18: 1926-30 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.127
BindingDB Entry DOI: 10.7270/Q20P10V3
More data for this
Ligand-Target Pair