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SMILES: CS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(Br)cc12)-c1ccc(F)cc1

InChI Key: InChIKey=YADMBOONGRGHEI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236311   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50236311
PNG
(4-(5-bromo-2-(4-fluorophenyl)-1H-indol-3-yl)-N-(me...)
Show SMILES CS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(Br)cc12)-c1ccc(F)cc1
Show InChI InChI=1S/C19H18BrFN2O3S/c1-27(25,26)23-18(24)4-2-3-15-16-11-13(20)7-10-17(16)22-19(15)12-5-8-14(21)9-6-12/h5-11,22H,2-4H2,1H3,(H,23,24)
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n/an/a 170n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay

Bioorg Med Chem Lett 18: 1926-30 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.127
BindingDB Entry DOI: 10.7270/Q20P10V3
More data for this
Ligand-Target Pair