BDBM50236733 CHEMBL4096680

SMILES: NS(=O)(=O)c1cccc2C(=O)C(Nc3ccccc3N3CCNCC3)=CC(=O)c12

InChI Key: InChIKey=OESYHAALOVZISZ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236733   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50236733 (CHEMBL4096680) Show SMILES NS(=O)(=O)c1cccc2C(=O)C(Nc3ccccc3N3CCNCC3)=CC(=O)c12 |c:26| Show InChI InChI=1S/C20H20N4O4S/c21-29(27,28)18-7-3-4-13-19(18)17(25)12-15(20(13)26)23-14-5-1-2-6-16(14)24-10-8-22-9-11-24/h1-7,12,22-23H,8-11H2,(H2,21,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Displacement of 5-FAM-SpYLPQTV from STAT3 (unknown origin) at pY705 site after 30 mins by fluorescence polarization assay				J Med Chem 60: 2718-2731 (2017) Article DOI: 10.1021/acs.jmedchem.6b01489 BindingDB Entry DOI: 10.7270/Q2N3007P
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50236733 (CHEMBL4096680) Show SMILES NS(=O)(=O)c1cccc2C(=O)C(Nc3ccccc3N3CCNCC3)=CC(=O)c12 |c:26| Show InChI InChI=1S/C20H20N4O4S/c21-29(27,28)18-7-3-4-13-19(18)17(25)12-15(20(13)26)23-14-5-1-2-6-16(14)24-10-8-22-9-11-24/h1-7,12,22-23H,8-11H2,(H2,21,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Antagonist activity against human progesterone receptor (hPR) in T47D human breast cancer cell line				J Med Chem 60: 2718-2731 (2017) Article DOI: 10.1021/acs.jmedchem.6b01489 BindingDB Entry DOI: 10.7270/Q2N3007P
					More data for this Ligand-Target Pair