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SMILES: CN1CCN(Cc2cn(c3ccccc23)S(=O)(=O)c2ccccc2F)CC1

InChI Key: InChIKey=BRNCKQRQEVEDIM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236810   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50236810
PNG
(CHEMBL4103281)
Show SMILES CN1CCN(Cc2cn(c3ccccc23)S(=O)(=O)c2ccccc2F)CC1
Show InChI InChI=1S/C20H22FN3O2S/c1-22-10-12-23(13-11-22)14-16-15-24(19-8-4-2-6-17(16)19)27(25,26)20-9-5-3-7-18(20)21/h2-9,15H,10-14H2,1H3
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Similars
Article
PubMed
 7.80n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins

J Med Chem 60: 1843-1859 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01662
BindingDB Entry DOI: 10.7270/Q27S7R1X
More data for this
Ligand-Target Pair