BDBM50236898 (1S,2R)-(+)-2-phenylcyclopropylamine::CHEMBL257990::TRANYLCYPROMINE::Tranylcypromine (TCP)::trans-2-phenylcyclopropanamine::trans-2-phenylcyclopropylamine

SMILES: N[C@H]1C[C@@H]1c1ccccc1

InChI Key: InChIKey=AELCINSCMGFISI-BDAKNGLRSA-N

Data: 9 KI  24 IC50  1 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 50236898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database									Mol Pharmacol 13: 454-73 (1977) BindingDB Entry DOI: 10.7270/Q2TT4PFZ
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database									Mol Pharmacol 13: 454-73 (1977) BindingDB Entry DOI: 10.7270/Q2TT4PFZ
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of MAO B				J Med Chem 54: 8236-50 (2011) Article DOI: 10.1021/jm201048w BindingDB Entry DOI: 10.7270/Q2D50NFR
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.66E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...				Bioorg Med Chem 19: 3709-16 (2011) Article DOI: 10.1016/j.bmc.2011.02.017 BindingDB Entry DOI: 10.7270/Q2J38SWT
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.81E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...				Bioorg Med Chem 19: 3709-16 (2011) Article DOI: 10.1016/j.bmc.2011.02.017 BindingDB Entry DOI: 10.7270/Q2J38SWT
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.02E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of MAO A				J Med Chem 54: 8236-50 (2011) Article DOI: 10.1021/jm201048w BindingDB Entry DOI: 10.7270/Q2D50NFR
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.68E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Inhibition of human truncated LSD1 lacking N-terminal 184 amino acids				Bioorg Med Chem 19: 3709-16 (2011) Article DOI: 10.1016/j.bmc.2011.02.017 BindingDB Entry DOI: 10.7270/Q2J38SWT
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.43E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of LSD1				J Med Chem 54: 8236-50 (2011) Article DOI: 10.1021/jm201048w BindingDB Entry DOI: 10.7270/Q2D50NFR
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.84E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Inhibition of human truncated LSD1 lacking N-terminal 184 amino acids				Bioorg Med Chem 19: 3709-16 (2011) Article DOI: 10.1016/j.bmc.2011.02.017 BindingDB Entry DOI: 10.7270/Q2J38SWT
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin)				J Med Chem 59: 253-63 (2016) BindingDB Entry DOI: 10.7270/Q23J3FSW
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of rat MAO-A using serotonin as substrate incubated for 1 hr				J Med Chem 59: 253-63 (2016) BindingDB Entry DOI: 10.7270/Q23J3FSW
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...				J Med Chem 59: 1531-44 (2016) BindingDB Entry DOI: 10.7270/Q2JH3P22
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...				J Med Chem 59: 1531-44 (2016) BindingDB Entry DOI: 10.7270/Q2JH3P22
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...				J Med Chem 59: 1531-44 (2016) BindingDB Entry DOI: 10.7270/Q2JH3P22
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Inhibition of partially purified LSD1 using histone H3K4Me2 peptide substrate by peroxidase-coupled assay				Bioorg Med Chem 19: 3702-8 (2011) Article DOI: 10.1016/j.bmc.2010.12.024 BindingDB Entry DOI: 10.7270/Q29K4BKJ
					More data for this Ligand-Target Pair
trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...				Bioorg Med Chem 16: 7415-23 (2008) Article DOI: 10.1016/j.bmc.2008.06.009 BindingDB Entry DOI: 10.7270/Q2DR2V92
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.51	n/a	n/a	n/a	n/a	n/a	25
China Pharmaceutical University					Assay Description The MAO-A and MAO-B screening biochemical assay was completed by Reaction Biology Corp. with the same assay format with LSD1 assay, and the detailed ...				Chem Biol Drug Des 85: 659-71 (2015) Article DOI: 10.1111/cbdd.12461 BindingDB Entry DOI: 10.7270/Q2GF0S73
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of LSD1				J Med Chem 52: 4551-73 (2009) Article DOI: 10.1021/jm900187v BindingDB Entry DOI: 10.7270/Q2RB77DT
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64.6	n/a	n/a	n/a	n/a	n/a	25
China Pharmaceutical University					Assay Description The MAO-A and MAO-B screening biochemical assay was completed by Reaction Biology Corp. with the same assay format with LSD1 assay, and the detailed ...				Chem Biol Drug Des 85: 659-71 (2015) Article DOI: 10.1111/cbdd.12461 BindingDB Entry DOI: 10.7270/Q2GF0S73
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.64E+3	n/a	n/a	n/a	n/a	7.5	25
China Pharmaceutical University					Assay Description Briefly, the compounds in DMSO were added into the LSD1 in the reaction buffer consisting of 50 mM Tris¿HCl, pH 7.5, and 1% DMSO, using Acoustic Tech...				Chem Biol Drug Des 85: 659-71 (2015) Article DOI: 10.1111/cbdd.12461 BindingDB Entry DOI: 10.7270/Q2GF0S73
					More data for this Ligand-Target Pair
Cytochrome P450 2B6 (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP2B6				J Med Chem 51: 2158-69 (2008) Article DOI: 10.1021/jm701447v BindingDB Entry DOI: 10.7270/Q29G5NPZ
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 51: 2158-69 (2008) Article DOI: 10.1021/jm701447v BindingDB Entry DOI: 10.7270/Q29G5NPZ
					More data for this Ligand-Target Pair
Bile salt export pump (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...				Drug Metab Dispos 40: 2332-41 (2012) Article DOI: 10.1124/dmd.112.047068 BindingDB Entry DOI: 10.7270/Q2ZP488M
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of MAO-A (unknown origin) using beetle luciferin derived luminogenic substrate preincubated for 15 mins followed by substrate addition mea...				Eur J Med Chem 144: 52-67 (2018) Article DOI: 10.1016/j.ejmech.2017.12.001 BindingDB Entry DOI: 10.7270/Q20V8GGB
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Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin)				Eur J Med Chem 144: 52-67 (2018) Article DOI: 10.1016/j.ejmech.2017.12.001 BindingDB Entry DOI: 10.7270/Q20V8GGB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of GST-tagged LSD1 (2 to 852 residues) (unknown origin) expressed in baculovirus infected sf9 cells preincubated for 15 mins followed by H...				Eur J Med Chem 144: 52-67 (2018) Article DOI: 10.1016/j.ejmech.2017.12.001 BindingDB Entry DOI: 10.7270/Q20V8GGB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated recombinant human LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3 (1 to 21 residues) K4m...				Bioorg Med Chem 26: 4871-4880 (2018) Article DOI: 10.1016/j.bmc.2018.08.026 BindingDB Entry DOI: 10.7270/Q2PR7ZN5
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Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhengzhou University Curated by ChEMBL					Assay Description Dissociation constant against galectin-3 using competitive fluorescence polarization				Eur J Med Chem 125: 940-951 (2017) Article DOI: 10.1016/j.ejmech.2016.10.021 BindingDB Entry DOI: 10.7270/Q2ZC8597
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Thrombin & trypsin (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.32E+7	n/a	n/a	n/a	n/a	n/a
Harvard University Curated by ChEMBL					Assay Description Binding affinity against trypsin				J Med Chem 45: 2770-80 (2002) Article DOI: 10.1021/jm0105833 BindingDB Entry DOI: 10.7270/Q2MG7S8S
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REST corepressor 1 (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of recombinant LSD1/CoREST (unknown origin) assessed as residual activity for 30 mins to 4 hrs by fluorescence based assay relative to con...				Medchemcomm 5: 1863-1870 (2014) Article DOI: 10.1039/c4md00283k BindingDB Entry DOI: 10.7270/Q2Q81H3T
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Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of MAOB (unknown origin) by luminiscent assay				Medchemcomm 5: 1863-1870 (2014) Article DOI: 10.1039/c4md00283k BindingDB Entry DOI: 10.7270/Q2Q81H3T
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of MAOA (unknown origin) by luminiscent assay				Medchemcomm 5: 1863-1870 (2014) Article DOI: 10.1039/c4md00283k BindingDB Entry DOI: 10.7270/Q2Q81H3T
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität Münster Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				Bioorg Med Chem 16: 7148-66 (2008) Article DOI: 10.1016/j.bmc.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CN73QW
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität Münster Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOB				Bioorg Med Chem 16: 7148-66 (2008) Article DOI: 10.1016/j.bmc.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CN73QW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of rat MAO-B using benzylamine as substrate				J Med Chem 59: 253-63 (2016) BindingDB Entry DOI: 10.7270/Q23J3FSW
					More data for this Ligand-Target Pair