BDBM50236934 CHEMBL4083908

SMILES: CCC[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CCc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1

InChI Key: InChIKey=UWLDODQTTHDXRJ-DTXPUJKBSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236934   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50236934 (CHEMBL4083908) Show SMILES CCC[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CCc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1 |r| Show InChI InChI=1S/C37H45N7O4S/c1-2-12-29(34(47)42-28(18-11-24-40-37(38)39)33(46)36-44-27-17-9-10-19-31(27)49-36)43-35(48)30(22-20-25-13-5-3-6-14-25)41-32(45)23-21-26-15-7-4-8-16-26/h3-10,13-17,19,28-30H,2,11-12,18,20-24H2,1H3,(H,41,45)(H,42,47)(H,43,48)(H4,38,39,40)/t28-,29-,30-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...				Eur J Med Chem 129: 110-123 (2017) Article DOI: 10.1016/j.ejmech.2017.02.006 BindingDB Entry DOI: 10.7270/Q2GB269P
					More data for this Ligand-Target Pair
Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50236934 (CHEMBL4083908) Show SMILES CCC[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CCc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1 |r| Show InChI InChI=1S/C37H45N7O4S/c1-2-12-29(34(47)42-28(18-11-24-40-37(38)39)33(46)36-44-27-17-9-10-19-31(27)49-36)43-35(48)30(22-20-25-13-5-3-6-14-25)41-32(45)23-21-26-15-7-4-8-16-26/h3-10,13-17,19,28-30H,2,11-12,18,20-24H2,1H3,(H,41,45)(H,42,47)(H,43,48)(H4,38,39,40)/t28-,29-,30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Inhibition of recombinant human matriptase (596 to 855 residues) expressed in Escherichia coli using Boc-Gln-Ala-ArgAMC as substrate measured for 120...				Eur J Med Chem 129: 110-123 (2017) Article DOI: 10.1016/j.ejmech.2017.02.006 BindingDB Entry DOI: 10.7270/Q2GB269P
					More data for this Ligand-Target Pair