BDBM50236990 CHEMBL4080590

SMILES: CNC(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)nnc1Cl

InChI Key: InChIKey=BJYZYCDBIWVFEN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50236990 (CHEMBL4080590) Show SMILES CNC(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)nnc1Cl Show InChI InChI=1S/C20H21ClN6O4/c1-22-19(28)12-7-5-6-8-13(12)24-18-17(21)26-27-20(25-18)23-11-9-14(29-2)16(31-4)15(10-11)30-3/h5-10H,1-4H3,(H,22,28)(H2,23,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris Descartes Curated by ChEMBL					Assay Description Inhibition of FAK (unknown origin) using Ulight-poly(Glu:Tyr)(4:1) as substrate after 1.6 hrs by TR-FRET assay				Bioorg Med Chem Lett 27: 1727-1730 (2017) Article DOI: 10.1016/j.bmcl.2017.02.072 BindingDB Entry DOI: 10.7270/Q2ZC855F
					More data for this Ligand-Target Pair