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BDBM50237009 CHEMBL4085357

SMILES: Fc1cnc(nc1N(CCOc1ccc(Cl)cc1)Cc1ccc2OCOc2c1)C#N

InChI Key: InChIKey=AVAFNPHGLHNISR-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237009   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Procathepsin L


(Homo sapiens (Human))		BDBM50237009
PNG
(CHEMBL4085357)
Show SMILES Fc1cnc(nc1N(CCOc1ccc(Cl)cc1)Cc1ccc2OCOc2c1)C#N
Show InChI InChI=1S/C21H16ClFN4O3/c22-15-2-4-16(5-3-15)28-8-7-27(21-17(23)11-25-20(10-24)26-21)12-14-1-6-18-19(9-14)30-13-29-18/h1-6,9,11H,7-8,12-13H2
PDB
MMDB

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Similars
Article
PubMed
 167n/an/an/an/an/an/an/an/a



Roche Pharmaceutical Research and Early Development (pRED)

Curated by ChEMBL


Assay Description
Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysis

J Med Chem 60: 2485-2497 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01881
BindingDB Entry DOI: 10.7270/Q2PV6NN3
More data for this
Ligand-Target Pair