BDBM50237025 CHEMBL4093759

SMILES: Fc1cnc(nc1N(CCc1ccncc1)Cc1ccc2OCOc2c1)C#N

InChI Key: InChIKey=IDQMJQGGMCEHMG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Procathepsin L (Homo sapiens (Human))	BDBM50237025 (CHEMBL4093759) Show SMILES Fc1cnc(nc1N(CCc1ccncc1)Cc1ccc2OCOc2c1)C#N Show InChI InChI=1S/C20H16FN5O2/c21-16-11-24-19(10-22)25-20(16)26(8-5-14-3-6-23-7-4-14)12-15-1-2-17-18(9-15)28-13-27-17/h1-4,6-7,9,11H,5,8,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	505	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharmaceutical Research and Early Development (pRED) Curated by ChEMBL					Assay Description Binding affinity for dopamine D4-like receptor labelled with [3H]YM-09151-2 in retina				J Med Chem 60: 2485-2497 (2017) Article DOI: 10.1021/acs.jmedchem.6b01881 BindingDB Entry DOI: 10.7270/Q2PV6NN3
					More data for this Ligand-Target Pair