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BDBM50237034 CHEMBL4061626

SMILES: Fc1cnc(nc1N(CC1CCCC1)Cc1ccc2OCOc2c1)C#N

InChI Key: InChIKey=QUYCPKSKEQMYOV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237034   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Procathepsin L


(Homo sapiens (Human))		BDBM50237034
PNG
(CHEMBL4061626)
Show SMILES Fc1cnc(nc1N(CC1CCCC1)Cc1ccc2OCOc2c1)C#N
Show InChI InChI=1S/C19H19FN4O2/c20-15-9-22-18(8-21)23-19(15)24(10-13-3-1-2-4-13)11-14-5-6-16-17(7-14)26-12-25-16/h5-7,9,13H,1-4,10-12H2
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MMDB

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Similars
Article
PubMed
 12n/an/an/an/an/an/an/an/a



Roche Pharmaceutical Research and Early Development (pRED)

Curated by ChEMBL


Assay Description
Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysis

J Med Chem 60: 2485-2497 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01881
BindingDB Entry DOI: 10.7270/Q2PV6NN3
More data for this
Ligand-Target Pair