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SMILES: [Na+].Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccc(Oc3ccc(F)cc3)cc2)cc1S([O-])(=O)=O

InChI Key: InChIKey=ZJMIBWMUXSTXHI-UHFFFAOYSA-M

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237580   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2Y purinoceptor 4


(Homo sapiens (Human))		BDBM50237580
PNG
(CHEMBL4074456)
Show SMILES [Na+].Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccc(Oc3ccc(F)cc3)cc2)cc1S([O-])(=O)=O
Show InChI InChI=1S/C26H17FN2O6S/c27-14-5-9-16(10-6-14)35-17-11-7-15(8-12-17)29-20-13-21(36(32,33)34)24(28)23-22(20)25(30)18-3-1-2-4-19(18)26(23)31/h1-13,29H,28H2,(H,32,33,34)/p-1
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Article
PubMed
n/an/a 1.69E+3n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human P2Y4 receptor transfected in human 1321N1 cells assessed as inhibition of UTP-activated intracellular calcium mobilizati...

J Med Chem 60: 3020-3038 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00030
BindingDB Entry DOI: 10.7270/Q2G73H15
More data for this
Ligand-Target Pair