null

SMILES: Oc1ccc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2c1

InChI Key: InChIKey=WNLKKLCKMRDNHF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50237597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase beta (Rattus norvegicus)	BDBM50237597 (7-hydroxy-3,7'-dicoumaryl ether | 7-hydroxy-3-(2-o...) Show SMILES Oc1ccc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2c1 Show InChI InChI=1S/C18H10O6/c19-12-4-1-11-7-16(18(21)24-14(11)8-12)22-13-5-2-10-3-6-17(20)23-15(10)9-13/h1-9,19H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of lyase activity of rat DNA polymerase beta after 30 mins				J Nat Prod 67: 1608-10 (2004) Article DOI: 10.1021/np040127s BindingDB Entry DOI: 10.7270/Q2JH3KZG
					More data for this Ligand-Target Pair
DNA polymerase beta (Homo sapiens (Human))	BDBM50237597 (7-hydroxy-3,7'-dicoumaryl ether | 7-hydroxy-3-(2-o...) Show SMILES Oc1ccc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2c1 Show InChI InChI=1S/C18H10O6/c19-12-4-1-11-7-16(18(21)24-14(11)8-12)22-13-5-2-10-3-6-17(20)23-15(10)9-13/h1-9,19H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of polymerase activity of DNA polymerase beta				Bioorg Med Chem 16: 4331-40 (2008) Article DOI: 10.1016/j.bmc.2008.02.071 BindingDB Entry DOI: 10.7270/Q2FX7BB7
					More data for this Ligand-Target Pair
DNA polymerase beta (Homo sapiens (Human))	BDBM50237597 (7-hydroxy-3,7'-dicoumaryl ether | 7-hydroxy-3-(2-o...) Show SMILES Oc1ccc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2c1 Show InChI InChI=1S/C18H10O6/c19-12-4-1-11-7-16(18(21)24-14(11)8-12)22-13-5-2-10-3-6-17(20)23-15(10)9-13/h1-9,19H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of lyase activity of DNA polymerase beta				Bioorg Med Chem 16: 4331-40 (2008) Article DOI: 10.1016/j.bmc.2008.02.071 BindingDB Entry DOI: 10.7270/Q2FX7BB7
					More data for this Ligand-Target Pair