BDBM50237674 CHEMBL4099816

SMILES: COC(=O)C1=C(Nc2cncnc2)O\C(=C/c2c[nH]c3ncccc23)C1=O

InChI Key: InChIKey=KMOQCJUVHSIAGZ-ACAGNQJTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDC7 and DBF4 (Homo sapiens (Human))	BDBM50237674 (CHEMBL4099816) Show SMILES COC(=O)C1=C(Nc2cncnc2)O\C(=C/c2c[nH]c3ncccc23)C1=O |c:4| Show InChI InChI=1S/C18H13N5O4/c1-26-18(25)14-15(24)13(27-17(14)23-11-7-19-9-20-8-11)5-10-6-22-16-12(10)3-2-4-21-16/h2-9,23H,1H3,(H,21,22)/b13-5-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Carna Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of 1 nM AVP-induced cAMP accumulation in cells expressing human vasopressin V2 receptor				Eur J Med Chem 130: 406-418 (2017) Article DOI: 10.1016/j.ejmech.2017.02.030 BindingDB Entry DOI: 10.7270/Q2X63Q71
					More data for this Ligand-Target Pair