BDBM50237675 CHEMBL4087825

SMILES: COC(=O)C1=C(Nc2cc[nH]n2)O\C(=C/c2c[nH]c3ncccc23)C1=O

InChI Key: InChIKey=ROLCHEVCTYPUAG-XFFZJAGNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDC7 and DBF4 (Homo sapiens (Human))	BDBM50237675 (CHEMBL4087825) Show SMILES COC(=O)C1=C(Nc2cc[nH]n2)O\C(=C/c2c[nH]c3ncccc23)C1=O |c:4| Show InChI InChI=1S/C17H13N5O4/c1-25-17(24)13-14(23)11(26-16(13)21-12-4-6-20-22-12)7-9-8-19-15-10(9)3-2-5-18-15/h2-8H,1H3,(H,18,19)(H2,20,21,22)/b11-7-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Carna Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus expression syst...				Eur J Med Chem 130: 406-418 (2017) Article DOI: 10.1016/j.ejmech.2017.02.030 BindingDB Entry DOI: 10.7270/Q2X63Q71
					More data for this Ligand-Target Pair