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BDBM50237945 CHEMBL4070218

SMILES: Cc1c(C#N)c(=O)oc2cc(OS(=O)(=O)c3ccc(Cl)cc3)ccc12

InChI Key:

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50237945   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens (Human))
BDBM50237945
PNG
(CHEMBL4070218)
Show SMILES Cc1c(C#N)c(=O)oc2cc(OS(=O)(=O)c3ccc(Cl)cc3)ccc12
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.52E+3n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Agonistic activity measures the ability to induce alkaline phosphatase in T47D human breast cancer cell line


Eur J Med Chem 131: 29-47 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.003
BindingDB Entry DOI: 10.7270/Q2MS3W2X
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Homo sapiens (Human))
BDBM50237945
PNG
(CHEMBL4070218)
Show SMILES Cc1c(C#N)c(=O)oc2cc(OS(=O)(=O)c3ccc(Cl)cc3)ccc12
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.03E+3n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 5-6 nM


Eur J Med Chem 131: 29-47 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.003
BindingDB Entry DOI: 10.7270/Q2MS3W2X
More data for this
Ligand-Target Pair