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SMILES: COc1cccc2nccc(Nc3ccnc(c3)-c3cc(Cl)ccc3F)c12

InChI Key: InChIKey=ZUAWZUMGCDPUHA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50238087   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TGF-beta receptor type-1


(Homo sapiens (Human))		BDBM50238087
PNG
(CHEMBL4077722)
Show SMILES COc1cccc2nccc(Nc3ccnc(c3)-c3cc(Cl)ccc3F)c12
Show InChI InChI=1S/C21H15ClFN3O/c1-27-20-4-2-3-17-21(20)18(8-10-24-17)26-14-7-9-25-19(12-14)15-11-13(22)5-6-16(15)23/h2-12H,1H3,(H,24,25,26)
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Similars
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of Angiotensin I converting enzyme

Bioorg Med Chem Lett 27: 1955-1961 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.026
BindingDB Entry DOI: 10.7270/Q2QJ7KKZ
More data for this
Ligand-Target Pair