BDBM50238276 CHEMBL4075037

SMILES: [H][C@]12C[C@@]1([H])N([C@@H](C2)C(=O)Nc1cccc(OC)c1)C(=O)Nc1cn(C(N)=O)c2ccccc12

InChI Key: InChIKey=PGJSYZRUDFHSSL-GBLZOACLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50238276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM50238276 (CHEMBL4075037) Show SMILES [H][C@]12C[C@@]1([H])N([C@@H](C2)C(=O)Nc1cccc(OC)c1)C(=O)Nc1cn(C(N)=O)c2ccccc12 |r| Show InChI InChI=1S/C23H23N5O4/c1-32-15-6-4-5-14(11-15)25-21(29)20-10-13-9-19(13)28(20)23(31)26-17-12-27(22(24)30)18-8-3-2-7-16(17)18/h2-8,11-13,19-20H,9-10H2,1H3,(H2,24,30)(H,25,29)(H,26,31)/t13-,19-,20+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibition of recombinant human complement factor D catalytic domain using Z-Lys-thiobenzylester as substrate preincubated for 1 hr followed by subst...				J Med Chem 60: 5717-5735 (2017) Article DOI: 10.1021/acs.jmedchem.7b00425 BindingDB Entry DOI: 10.7270/Q2TB195V
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