BDBM50238308 CHEMBL4103605

SMILES: Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)c12

InChI Key: InChIKey=GIODDBAYPWNJIQ-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50238308   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238308 (CHEMBL4103605) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)c12 Show InChI InChI=1S/C21H19N5O/c1-13-4-3-5-17(12-13)24-21(27)23-16-8-6-15(7-9-16)18-10-11-22-20-19(18)14(2)25-26-20/h3-12H,1-2H3,(H,22,25,26)(H2,23,24,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50238308 (CHEMBL4103605) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)c12 Show InChI InChI=1S/C21H19N5O/c1-13-4-3-5-17(12-13)24-21(27)23-16-8-6-15(7-9-16)18-10-11-22-20-19(18)14(2)25-26-20/h3-12H,1-2H3,(H,22,25,26)(H2,23,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50238308 (CHEMBL4103605) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)c12 Show InChI InChI=1S/C21H19N5O/c1-13-4-3-5-17(12-13)24-21(27)23-16-8-6-15(7-9-16)18-10-11-22-20-19(18)14(2)25-26-20/h3-12H,1-2H3,(H,22,25,26)(H2,23,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of FGFR1 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of AT...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50238308 (CHEMBL4103605) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)c12 Show InChI InChI=1S/C21H19N5O/c1-13-4-3-5-17(12-13)24-21(27)23-16-8-6-15(7-9-16)18-10-11-22-20-19(18)14(2)25-26-20/h3-12H,1-2H3,(H,22,25,26)(H2,23,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence o...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50238308 (CHEMBL4103605) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)c12 Show InChI InChI=1S/C21H19N5O/c1-13-4-3-5-17(12-13)24-21(27)23-16-8-6-15(7-9-16)18-10-11-22-20-19(18)14(2)25-26-20/h3-12H,1-2H3,(H,22,25,26)(H2,23,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of VEGFR1 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of A...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238308 (CHEMBL4103605) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)c12 Show InChI InChI=1S/C21H19N5O/c1-13-4-3-5-17(12-13)24-21(27)23-16-8-6-15(7-9-16)18-10-11-22-20-19(18)14(2)25-26-20/h3-12H,1-2H3,(H,22,25,26)(H2,23,24,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50238308 (CHEMBL4103605) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)c12 Show InChI InChI=1S/C21H19N5O/c1-13-4-3-5-17(12-13)24-21(27)23-16-8-6-15(7-9-16)18-10-11-22-20-19(18)14(2)25-26-20/h3-12H,1-2H3,(H,22,25,26)(H2,23,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	376	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of VEGFR3 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of A...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50238308 (CHEMBL4103605) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)c12 Show InChI InChI=1S/C21H19N5O/c1-13-4-3-5-17(12-13)24-21(27)23-16-8-6-15(7-9-16)18-10-11-22-20-19(18)14(2)25-26-20/h3-12H,1-2H3,(H,22,25,26)(H2,23,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of A...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair