BDBM50238882 CHEMBL4094600
SMILES: C[C@@H](c1ccccc1)n1nnc2cnc3ccc(cc3c12)-c1ccnc(C)c1
InChI Key: InChIKey=IJELDUSMVKXTCW-INIZCTEOSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity protein kinase CLK1/CLK4 (Homo sapiens (Human)) | BDBM50238882 (CHEMBL4094600) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University and Collaborative Innovation Center for Biotherapy Curated by ChEMBL | Assay Description Inhibition of recombinant human CLK1 expressed in insect cells using ERMRPRKRQGSVRRRV peptide as substrate after 40 mins in presence of [gamma-33P]-A... | J Med Chem 60: 6337-6352 (2017) Article DOI: 10.1021/acs.jmedchem.7b00665 BindingDB Entry DOI: 10.7270/Q2ZW1P55 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human)) | BDBM50238882 (CHEMBL4094600) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 177 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University and Collaborative Innovation Center for Biotherapy Curated by ChEMBL | Assay Description Inhibition of recombinant human DYRK1A expressed in insect cells using RRRFRPASPLRGPPK peptide as substrate after 40 mins in presence of [gamma-33P]-... | J Med Chem 60: 6337-6352 (2017) Article DOI: 10.1021/acs.jmedchem.7b00665 BindingDB Entry DOI: 10.7270/Q2ZW1P55 | |||||||||||
More data for this Ligand-Target Pair |