BDBM50238893 CHEMBL4096379

SMILES: Cc1cc(ccn1)-c1ccc2ncc3nnn(Cc4ccc(F)cc4)c3c2c1

InChI Key: InChIKey=SBZWDKFEGYDKIU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50238893   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase CLK1/CLK4 (Homo sapiens (Human))	BDBM50238893 (CHEMBL4096379) Show SMILES Cc1cc(ccn1)-c1ccc2ncc3nnn(Cc4ccc(F)cc4)c3c2c1 Show InChI InChI=1S/C22H16FN5/c1-14-10-17(8-9-24-14)16-4-7-20-19(11-16)22-21(12-25-20)26-27-28(22)13-15-2-5-18(23)6-3-15/h2-12H,13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University and Collaborative Innovation Center for Biotherapy Curated by ChEMBL					Assay Description Inhibition of recombinant human CLK1 expressed in insect cells using ERMRPRKRQGSVRRRV peptide as substrate after 40 mins in presence of [gamma-33P]-A...				J Med Chem 60: 6337-6352 (2017) Article DOI: 10.1021/acs.jmedchem.7b00665 BindingDB Entry DOI: 10.7270/Q2ZW1P55
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50238893 (CHEMBL4096379) Show SMILES Cc1cc(ccn1)-c1ccc2ncc3nnn(Cc4ccc(F)cc4)c3c2c1 Show InChI InChI=1S/C22H16FN5/c1-14-10-17(8-9-24-14)16-4-7-20-19(11-16)22-21(12-25-20)26-27-28(22)13-15-2-5-18(23)6-3-15/h2-12H,13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University and Collaborative Innovation Center for Biotherapy Curated by ChEMBL					Assay Description Inhibition of recombinant human DYRK1A expressed in insect cells using RRRFRPASPLRGPPK peptide as substrate after 40 mins in presence of [gamma-33P]-...				J Med Chem 60: 6337-6352 (2017) Article DOI: 10.1021/acs.jmedchem.7b00665 BindingDB Entry DOI: 10.7270/Q2ZW1P55
					More data for this Ligand-Target Pair