BDBM50238897 CHEMBL4067361

SMILES: CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)c3ccc(cc3oc2c1)=[N+](CC)CC

InChI Key: InChIKey=PGHVVJPXLMHXBA-LHEWISCISA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50238897   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50238897 (CHEMBL4067361) Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)c3ccc(cc3oc2c1)=[N+](CC)CC |r,wD:19.20,(23.05,-44.14,;21.72,-43.36,;21.72,-41.82,;23.05,-41.05,;24.38,-41.82,;20.37,-41.05,;20.36,-39.52,;19.03,-38.75,;17.71,-39.53,;16.37,-38.76,;16.36,-36.7,;15.01,-35.94,;15.01,-34.4,;16.34,-33.62,;17.67,-34.39,;17.67,-35.92,;19.01,-36.69,;19.01,-38.25,;20.36,-35.92,;21.71,-36.69,;21.71,-38.25,;23.05,-39.02,;23.05,-40.56,;24.38,-41.33,;25.71,-40.56,;23.06,-35.92,;23.06,-34.37,;24.41,-36.69,;24.41,-38.23,;25.75,-39,;27.08,-38.23,;28.41,-38.99,;27.07,-36.69,;25.74,-35.92,;25.73,-34.38,;27.07,-33.62,;27.07,-32.08,;25.73,-31.31,;24.39,-32.09,;24.4,-33.63,;15.03,-39.55,;13.7,-38.79,;12.38,-39.56,;12.4,-41.11,;13.72,-41.86,;15.04,-41.09,;16.38,-41.85,;17.71,-41.07,;19.05,-41.84,;11.05,-41.88,;9.71,-41.11,;8.38,-41.88,;11.05,-43.42,;9.71,-44.19,)| Show InChI InChI=1S/C44H54N6O4/c1-5-48(6-2)32-21-23-36-39(28-32)54-40-29-33(49(7-3)8-4)22-24-37(40)42(36)34-18-12-13-19-35(34)43(52)47-38(20-14-15-26-45)44(53)50(27-25-41(46)51)30-31-16-10-9-11-17-31/h9-13,16-19,21-24,28-29,38H,5-8,14-15,20,25-27,30,45H2,1-4H3,(H2-,46,47,51,52)/p+1/t38-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	759	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...				J Med Chem 60: 6991-6997 (2017) Article DOI: 10.1021/acs.jmedchem.7b00489 BindingDB Entry DOI: 10.7270/Q2V40XFR
					More data for this Ligand-Target Pair