BDBM50239848 CHEMBL4098897

SMILES: CCCOc1cncc2nnc(-c3c[nH]nc3-c3ccc(cc3)C(F)(F)F)n12

InChI Key: InChIKey=DFYKORKCCWNTDS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239848   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50239848 (CHEMBL4098897) Show SMILES CCCOc1cncc2nnc(-c3c[nH]nc3-c3ccc(cc3)C(F)(F)F)n12 Show InChI InChI=1S/C18H15F3N6O/c1-2-7-28-15-10-22-9-14-24-26-17(27(14)15)13-8-23-25-16(13)11-3-5-12(6-4-11)18(19,20)21/h3-6,8-10H,2,7H2,1H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant human FLAG-tagged PDE2A3 expressed in sf21 cells using [3H]cGMP as substrate by scintillation proximity assay				J Med Chem 60: 5673-5698 (2017) Article DOI: 10.1021/acs.jmedchem.7b00397 BindingDB Entry DOI: 10.7270/Q2VX0JNT
					More data for this Ligand-Target Pair