BDBM50239855 CHEMBL4072920

SMILES: CCCOc1cncc2nnc(-c3cnn(C)c3-c3ccc(F)cc3)n12

InChI Key: InChIKey=WUYMEQRUUQGMFZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239855   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50239855 (CHEMBL4072920) Show SMILES CCCOc1cncc2nnc(-c3cnn(C)c3-c3ccc(F)cc3)n12 Show InChI InChI=1S/C18H17FN6O/c1-3-8-26-16-11-20-10-15-22-23-18(25(15)16)14-9-21-24(2)17(14)12-4-6-13(19)7-5-12/h4-7,9-11H,3,8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	241	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant human FLAG-tagged PDE2A3 expressed in sf21 cells using [3H]cGMP as substrate by scintillation proximity assay				J Med Chem 60: 5673-5698 (2017) Article DOI: 10.1021/acs.jmedchem.7b00397 BindingDB Entry DOI: 10.7270/Q2VX0JNT
					More data for this Ligand-Target Pair