BDBM50239868 CHEMBL4097764

SMILES: O=C1Nc2cc(=O)n(Cc3ccccc3)cc2CN1c1cccc(OCc2cccnc2)c1

InChI Key: InChIKey=PSWMJOPGLAUUCC-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239868   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
U5 small nuclear ribonucleoprotein 200 kDa helicase (Homo sapiens (Human))	BDBM50239868 (CHEMBL4097764) Show SMILES O=C1Nc2cc(=O)n(Cc3ccccc3)cc2CN1c1cccc(OCc2cccnc2)c1 Show InChI InChI=1S/C26H22N4O3/c31-25-13-24-21(16-29(25)15-19-6-2-1-3-7-19)17-30(26(32)28-24)22-9-4-10-23(12-22)33-18-20-8-5-11-27-14-20/h1-14,16H,15,17-18H2,(H,28,32)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Takeda California Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...				J Med Chem 60: 5759-5771 (2017) Article DOI: 10.1021/acs.jmedchem.7b00461 BindingDB Entry DOI: 10.7270/Q2MC925G
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50239868 (CHEMBL4097764) Show SMILES O=C1Nc2cc(=O)n(Cc3ccccc3)cc2CN1c1cccc(OCc2cccnc2)c1 Show InChI InChI=1S/C26H22N4O3/c31-25-13-24-21(16-29(25)15-19-6-2-1-3-7-19)17-30(26(32)28-24)22-9-4-10-23(12-22)33-18-20-8-5-11-27-14-20/h1-14,16H,15,17-18H2,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Takeda California Inc. Curated by ChEMBL					Assay Description Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...				J Med Chem 60: 5759-5771 (2017) Article DOI: 10.1021/acs.jmedchem.7b00461 BindingDB Entry DOI: 10.7270/Q2MC925G
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-III (Homo sapiens (Human))	BDBM50239868 (CHEMBL4097764) Show SMILES O=C1Nc2cc(=O)n(Cc3ccccc3)cc2CN1c1cccc(OCc2cccnc2)c1 Show InChI InChI=1S/C26H22N4O3/c31-25-13-24-21(16-29(25)15-19-6-2-1-3-7-19)17-30(26(32)28-24)22-9-4-10-23(12-22)33-18-20-8-5-11-27-14-20/h1-14,16H,15,17-18H2,(H,28,32)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Takeda California Inc. Curated by ChEMBL					Assay Description Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...				J Med Chem 60: 5759-5771 (2017) Article DOI: 10.1021/acs.jmedchem.7b00461 BindingDB Entry DOI: 10.7270/Q2MC925G
					More data for this Ligand-Target Pair