BDBM50240132 CHEMBL4090898

SMILES: CN(C)CCCNC(=O)c1ccc2nnc3-c4ccccc4C(=O)c3c2c1

InChI Key: InChIKey=YQGXMAVVQJXVAC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50240132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50240132 (CHEMBL4090898) Show SMILES CN(C)CCCNC(=O)c1ccc2nnc3-c4ccccc4C(=O)c3c2c1 Show InChI InChI=1S/C21H20N4O2/c1-25(2)11-5-10-22-21(27)13-8-9-17-16(12-13)18-19(24-23-17)14-6-3-4-7-15(14)20(18)26/h3-4,6-9,12H,5,10-11H2,1-2H3,(H,22,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
National and Kapodistrian University of Athens Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2alpha-mediated kinetoplast DNA decatenation after 60 mins by ethidium bromide staining based agarose gel electroph...				Bioorg Med Chem 25: 2625-2634 (2017) Article DOI: 10.1016/j.bmc.2017.03.019 BindingDB Entry DOI: 10.7270/Q2FQ9ZS6
					More data for this Ligand-Target Pair